This is bad for us. Desai had that unit 25th in points allowed with the most insane DL. Patricia, at the very least, is highly multiple in nature on the DL. That alone will help the Eagles.
I'd look to have them in 3-4 all game with Carter, Davis, Cox in the middle and Sweat/Reddick on the edges. Taking advantage of all of that versatile talent, getting out of that lighter front, hurting our rushing attack (predicated heavily on IZ, IIRC) and trying to make either Lock or a seriously ailing Geno explicitly beat them through the air.
Bad week for this change to come up. Patricia, overall, is kind of a joke. But I think this bodes very negatively for our matchup.