Brees' first two full seasons with the Chargers were pretty rough, but his last two, although not sensational, were nevertheless very good as he had 51/22 TD/INT ratio, completed 65% of his passes, and threw for over 6700 yards. One can make the argument that Brees was a finished product before he and Sean Payton hooked up in the Big Easy.
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On the other hand, Lock has not had any stretch in his time with the Broncos that is anywhere close to what Brees did in his final two seasons with the Chargers, with a career TD/INT ratio of 25/20 and a sub 60% completion percentage.
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Better find another comparison.