This is an over-reaction to one game. Sean McDermott is a defensive mastermind, and he had a good game plan against the Seahawks. Still, if Connor Williams doesn't snap the ball over Geno's head or step on Geno's foot, it could have been a tied game at half-time. If you give a team like the Bills a lead, they will kill you. They have more 20-point wins than any other NFL teams this year.
There is nothing "college-like" about Grubb's offense. The problems with the running game are maddening, but run fits are no different conceptually in college than in the NFL. Grubb does seem to be using zone run concepts more than man blocking, which makes sense given our lack of talent on the offensive line, but that inside zone doesn't seem to be working at all. They don't seem to be creating even a small crease to run through. Maybe more outside zone concepts?
The Seahawks' offense is still in the top-10 in points scored and yards gained. Not saying the offense is great, because it has major problems on the O-line, but the real problem is the defense.