Tacoma-area women must've been lining up for blocks back in the day for a night with Papa Trufant. The dude's a machine. Forget his sons, this dude's sperm is golden and only produces NFL caliber cornerbacks. He is to the NFL what the elder Molina is to the MLB and the catcher position. That'd be a sick documentary right there. Just a ton of interviews and stories as told my Mr. Molina, Mr. Matthews, Mr. Trufant, etc... But I digress!
Back to your point pe. Desmond's a beast. The rare times I could catch UDub out in NYC (which proves your point about people out east not knowing who he is outside of the last name and most don't know who Marcus Trufant is either out here, idiots) I would always watch for Desmond and he would always impress. Like you said, he's just a natural out there. He's one of the few Huskies that I don't hate for no apparent reason.
I like that Asante Samuel comparison a lot, except I think he could actually end up better. Doesn't gamble as much as Samuel so he might not get as many picks but he also might not give up the big play as often.
The East Coast Bias sucks!