I think its almost a lock that we'll get one of the hyped up national primetime games. Either Sunday night or the 2nd half of the Monday night double header. I'm guessing the game will be played in Seattle because A: they'll want to highlight the best crowd in the NFL and B: they'll want to avoid the possibility of getting stabbed, shot, or beaten by going to Candlestick or whatever they call it these days.
Here's my prediction for the opening weeks Prime time games:
TNF: New England @ Baltimore
SNF: San Francisco @ Seattle
MNF1: Dallas @ Washington
MNF2: Denver @ San Diego
Or, the alternate if we get pushed to MNF because there's not many good teams out West
TNF: Pittsburgh @ Baltimore
SNF: Dallas @ Washington
MNF1: Denver @ New England
MNF2: San Francisco @ Seattle
Of course, if the Mariners are playing at home this weekend then we'll probably be on the road.