Win-win on the defenses. Heart says Seattle's, but gut says Packers'. If we decimated the Bears on the road as bad as we did, just think about what a supercharged Green Bay offense, fired up about losing last week, will do to them. And they're long-time division rivals. I don't think either one will be a terrible choice, but for pure domination, I'd go with Green Bays', as much as it pains me as a Seahawks fan to admit it.
With RB, you've again got a possible win-win, but not as likely. Marshawn could go on a tear after being shut down some against the Bears, but SF's defense is really good too. Better, in fact. And couple that with the fact that Mendenhall is on a team smarting from a Monday night thrashing, fighting for their division title against the hapless Rams, and you've got a winner there. Add the fact that a crippled Worthlessburger will only add to the run game, and you've got your answer here. Marshawn may well be a great choice for fantasy points this week, but Mendenhall in this case is a better one.
None of the WR choices are stellar ones, but you work with whatcha got. And it might be a little easier choice to make. I don't think I'd trust any KC receiver, even if it is against Chokeland. All of those teams are right in the thick of a division title slugfest, and it's anyone's game. They've all had great games, and they've all had craptastic games. KC is coming down off the high of beating the previously unbeaten Green Bay Packers, and may have a letdown game. Chokeland is hot then cold. Or more cold then cold lately, but still. Tate and Baldwin aren't guarantees to do anything with Jackson throwing to them against the stiff 49ers defense, but they're probably better than KC's WRs. Tate's been on a considerable upswing here at the end of the year, but Baldwin might rebound from an off game last week and continue his dominance as our leading receiver. It's a push for me between the two of them, but I might go with Tate to continue a late-season surge.
"The ultimate number is W's, and that’s what matters in Santa Clara. As such, Jed York does not own the 49ers; Russell Wilson does." - Paul Gutierrez