Oregon has been reliant on the Read Option for years. It is different than our read option - Oregon tends to run more of a slow developing read where the QB waits a long time before handing off/taking off - but it's the same basic philosophy.
Like any kind of option, the key is for the linebackers to remain disciplined and play gaps. Playing the linebackers back a yard or two has had some success vs Oregon (eff you Stanford), but you're going to give up more incremental gains that way unless the DL blows the play up (again, eff you Stanford). That might be difficult for such an aggressive defense, but I don't really expect their LBs to be too phased by it. The DL can screw up the play by getting inside penetration, like most runs, but an overaggressive DL can leave the LBs in a tough spot if they get too far upfield.
Aldon Smith should be the key. He's fast enough to chase down the ball carrier from seemingly anywhere near the LOS, but he's probably the player most likely to make a mental mistake, which could open some big runs.
Sarlacc, on comparing .NET to Soccer: And why not? It's a bunch of people running around in circles, feigning pain, and never scoring.